MED23

Gene

mediator complex subunit 23

HGNCHGNC:2372 EnsemblENSG00000112282 NCBI Gene9439

Locus: gene with protein productLocation: 6q23.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCRSP3 · MRT18 · CRSP130 · DRIP130 · Sur2

View full nomenclature history (7)

Previous symbolsCRSP3, MRT18

Alias symbolsCRSP130, DRIP130, Sur2

Previous namescofactor required for Sp1 transcriptional activation, subunit 3, 130kDa, mental retardation, non-syndromic, autosomal recessive, 18

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Autosomal recessive non-syndromic intellectual disability

Genetic Diseases, Inborn

Diabetes Mellitus, Type 2

Neurodegenerative Diseases

Metabolic Syndrome

Breast adenocarcinoma

Neurodevelopmental Disorders

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Mediator complex

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.