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MITF

Gene

melanocyte inducing transcription factor

HGNCHGNC:7105EnsemblENSG00000187098NCBI Gene4286
Locus: gene with protein productLocation: 3p13

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asWS2A · WS2 · MI · bHLHe32
View full nomenclature history (8)
Previous symbolsWS2A, WS2
Alias symbolsMI, bHLHe32
Previous namesWaardenburg syndrome, type 2A, microphthalmia-associated transcription factor, melanogenesis associated transcription factor
Alias nameshomolog of mouse microphthalmia

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Cutaneous melanoma
Hair color

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Basic helix-loop-helix proteins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-03-15.
Open TargetsGene–disease associations from the Open Targets Platform.