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MPZ

Gene

myelin protein zero

HGNCHGNC:7225EnsemblENSG00000158887NCBI Gene4359
Locus: gene with protein productLocation: 1q23.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCMT1 · CMT1B · HMSNIB · CMT2I · CMT2J · P0
View full nomenclature history (7)
Previous symbolsCMT1, CMT1B
Alias symbolsHMSNIB, CMT2I, CMT2J, P0
Previous namesCharcot-Marie-Tooth neuropathy 1B

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Charcot-Marie-Tooth Disease

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

V-set domain containingIg-like cell adhesion molecule family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.