MS4A1

Gene

membrane spanning 4-domains A1

HGNCHGNC:7315 EnsemblENSG00000156738 NCBI Gene931

Locus: gene with protein productLocation: 11q12.2

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

B-lymphocyte antigen CD20P11836

Protein · therapeutic target

Clinically validated target · 11 approved medicines against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCD20 · B1 · Bp35 · FMC7

View full nomenclature history (5)

Previous symbolsCD20

Alias symbolsB1, Bp35, FMC7

Previous namesmembrane-spanning 4-domains, subfamily A, member 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Leukemia, Lymphocytic, Chronic, B-Cell

Lymphoma, Large B-Cell, Diffuse

Lymphoma, Follicular

Arthritis, Rheumatoid

Lymphoma, Non-Hodgkin's

Multiple Sclerosis

Neoplasms

Precursor Cell Lymphoblastic Leukemia-Lymphoma

Granulomatosis with polyangiitis

Multiple Sclerosis, Relapsing-Remitting

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

CD moleculesMembrane spanning 4-domains

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.