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MT-CO1

Gene

mitochondrially encoded cytochrome c oxidase I

HGNCHGNC:7419EnsemblENSG00000198804NCBI Gene4512
Locus: gene with protein productLocation: mitochondria

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asMTCO1 · COX1 · COI
View full nomenclature history (4)
Previous symbolsMTCO1
Alias symbolsCOX1, COI
Previous namescytochrome c oxidase I

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Optic Atrophy, Hereditary, Leber
MERRF Syndrome

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Mitochondrial complex IV: cytochrome c oxidase subunitsMitochondrially encoded protein coding genes

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2021-05-26.
Open TargetsGene–disease associations from the Open Targets Platform.