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MT-CYB

Gene

mitochondrially encoded cytochrome b

HGNCHGNC:7427EnsemblENSG00000198727NCBI Gene4519
Locus: gene with protein productLocation: mitochondria

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asMTCYB · COB · CYTB · UQCR3
View full nomenclature history (5)
Previous symbolsMTCYB
Alias symbolsCOB, CYTB, UQCR3
Previous namescytochrome b

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Optic Atrophy, Hereditary, Leber

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Mitochondrial complex III: ubiquinol-cytochrome c reductase complex subunitsMitochondrially encoded protein coding genes

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2021-12-02.
Open TargetsGene–disease associations from the Open Targets Platform.