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MT-ND4L

Gene

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L

HGNCHGNC:7460EnsemblENSG00000212907NCBI Gene4539
Locus: gene with protein productLocation: mitochondria

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asMTND4L · ND4L · NAD4L
View full nomenclature history (7)
Previous symbolsMTND4L
Alias symbolsND4L, NAD4L
Previous namesNADH dehydrogenase 4L, mitochondrially encoded NADH dehydrogenase 4L
Alias namescomplex I ND4L subunit, NADH-ubiquinone oxidoreductase chain 4L

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Optic Atrophy, Hereditary, Leber
Diabetes Mellitus, Type 2
Diabetes Mellitus
MERRF Syndrome

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

NADH:ubiquinone oxidoreductase core subunitsMitochondrially encoded protein coding genes

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2021-05-26.
Open TargetsGene–disease associations from the Open Targets Platform.