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MT-ND5

Gene

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5

HGNCHGNC:7461EnsemblENSG00000198786NCBI Gene4540
Locus: gene with protein productLocation: mitochondria

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asMTND5 · ND5 · NAD5
View full nomenclature history (7)
Previous symbolsMTND5
Alias symbolsND5, NAD5
Previous namesmitochondrially encoded NADH dehydrogenase 5, NADH dehydrogenase 5
Alias namescomplex I ND5 subunit, NADH-ubiquinone oxidoreductase chain 5

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Optic Atrophy, Hereditary, Leber
MERRF Syndrome
Diabetes Mellitus, Type 2
Diabetes Mellitus

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

NADH:ubiquinone oxidoreductase core subunitsMitochondrially encoded protein coding genes

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2021-05-26.
Open TargetsGene–disease associations from the Open Targets Platform.