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MTTP

Gene

microsomal triglyceride transfer protein

HGNCHGNC:7467EnsemblENSG00000138823NCBI Gene4547
Locus: gene with protein productLocation: 4q23

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asMTP · ABL
View full nomenclature history (4)
Previous symbolsMTP
Alias symbolsABL
Previous namesmicrosomal triglyceride transfer protein (large polypeptide, 88kD), microsomal triglyceride transfer protein (large polypeptide, 88kDa)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Familial hypercholesterolemia
Genetic Diseases, Inborn
Cardiovascular Diseases
Metabolic Syndrome
Homozygous familial hypercholesterolemia
Liver Diseases
Non-alcoholic Fatty Liver Disease

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.