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MYC

Gene

MYC proto-oncogene, bHLH transcription factor

HGNCHGNC:7553EnsemblENSG00000136997NCBI Gene4609
Locus: gene with protein productLocation: 8q24.21

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asc-Myc · bHLHe39 · MYCC
View full nomenclature history (4)
Alias symbolsc-Myc, bHLHe39, MYCC
Previous namesv-myc avian myelocytomatosis viral oncogene homolog

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Burkitt Lymphoma
Neurodegenerative Diseases
Urinary bladder carcinoma
Urinary Bladder Neoplasms
Asthma
Prostate carcinoma
Diabetes Mellitus, Type 2
Lymphoma, Large B-Cell, Diffuse
Diabetes Mellitus
Lymphoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Basic helix-loop-helix proteins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.