MYH7

Gene

myosin heavy chain 7

HGNCHGNC:7577 EnsemblENSG00000092054 NCBI Gene4625

Locus: gene with protein productLocation: 14q11.2

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Myosin-7P12883

Protein · therapeutic target

Clinically validated target · 2 approved medicines against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCMH1 · MPD1 · CMD1S

View full nomenclature history (5)

Previous symbolsCMH1, MPD1

Alias symbolsCMD1S

Previous namesmyopathy, distal 1, myosin, heavy polypeptide 7, cardiac muscle, beta

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Cardiomyopathy, Hypertrophic

congenital myopathy 7A, myosin storage, autosomal dominant

Left ventricular noncompaction

MYH7-related skeletal myopathy

Hypertrophic cardiomyopathy 1

Cardiomyopathies

Cardiomyopathy, Dilated

Familial isolated dilated cardiomyopathy

Myopathy, myosin storage, autosomal recessive

Laing early-onset distal myopathy

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Myosin heavy chains, class IIMicroRNA protein coding host genes

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.