NAIP

Gene

NLR family apoptosis inhibitory protein

HGNCHGNC:7634 EnsemblENSG00000249437 NCBI Gene4671

Locus: gene with protein productLocation: 5q13.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asBIRC1 · NLRB1

View full nomenclature history (5)

Previous symbolsBIRC1

Alias symbolsNLRB1

Previous namesbaculoviral IAP repeat-containing 1

Alias namesNLR family, BIR domain containing 1, nucleotide-binding oligomerization domain, leucine rich repeat and BIR domain containing 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Spinal muscular atrophy, type 1

Proximal spinal muscular atrophy type 2

Spinal Muscular Atrophies of Childhood

Proximal spinal muscular atrophy

Amyotrophic Lateral Sclerosis

Breast Neoplasms

Infections

Salmonella Infections

Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Baculoviral IAP repeat containingNLR family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.