NAXE

Gene

NAD(P)HX epimerase

HGNCHGNC:18453 EnsemblENSG00000163382 NCBI Gene128240

Locus: gene with protein productLocation: 1q22

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asAPOA1BP · AIBP · MGC119143 · MGC119144 · MGC119145 · YJEFN1

View full nomenclature history (9)

Previous symbolsAPOA1BP

Alias symbolsAIBP, MGC119143, MGC119144, MGC119145, YJEFN1

Previous namesapolipoprotein A-I binding protein

Alias namesapoA-I binding protein, NAD(P)H-hydrate epimerase

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Encephalopathy, progressive, early-onset, with brain edema and/or leukoencephalopathy

Mitochondrial Diseases

Genetic Diseases, Inborn

Atrial Fibrillation

Carcinoma, Hepatocellular

Alzheimer's Disease

Neoplasms

Neutropenia

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.