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NBN

Gene

nibrin

HGNCHGNC:7652EnsemblENSG00000104320NCBI Gene4683
Locus: gene with protein productLocation: 8q21.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asNBS · NBS1 · ATV · AT-V2 · AT-V1
View full nomenclature history (6)
Previous symbolsNBS, NBS1
Alias symbolsATV, AT-V2, AT-V1
Previous namesNijmegen breakage syndrome 1 (nibrin)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Anemia, Aplastic
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Inherited cancer-predisposing syndrome
Neoplastic Syndromes, Hereditary
Neoplasms
Glioma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

BRCA1 C complexMRN complex

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.