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NCF1

Gene

neutrophil cytosolic factor 1

HGNCHGNC:7660EnsemblENSG00000158517NCBI Gene653361
Locus: gene with protein productLocation: 7q11.23

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asp47phox · NOXO2 · NCF1A · SH3PXD1A
View full nomenclature history (7)
Alias symbolsp47phox, NOXO2, NCF1A, SH3PXD1A
Previous namesneutrophil cytosolic factor 1 (47kD, chronic granulomatous disease, autosomal 1)
Alias namesNADPH oxidase organizer 2, chronic granulomatous disease, autosomal 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Granulomatous Disease, Chronic
Atrial Fibrillation
Neurodegenerative Diseases
Rare familial disorder with hypertrophic cardiomyopathy
Hypertension
Cardiovascular Diseases
Diabetes Mellitus, Type 2

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.