NDUFAF4

Gene

NADH:ubiquinone oxidoreductase complex assembly factor 4

HGNCHGNC:21034 EnsemblENSG00000123545 NCBI Gene29078

Locus: gene with protein productLocation: 6q16.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asC6orf66 · HSPC125 · bA22L21.1 · My013 · HRPAP20

View full nomenclature history (8)

Previous symbolsC6orf66

Alias symbolsHSPC125, bA22L21.1, My013, HRPAP20

Previous nameschromosome 6 open reading frame 66, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 4, NADH dehydrogenase (ubiquinone) complex I, assembly factor 4

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Mitochondrial Diseases

Neurodegenerative Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Mitochondrial respiratory chain complex assembly factors

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.