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NF2

Gene

NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor

HGNCHGNC:7773EnsemblENSG00000186575NCBI Gene4771
Locus: gene with protein productLocation: 22q12.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asmerlin · ACN · SCH · BANF · merlin-1
View full nomenclature history (10)
Alias symbolsmerlin, ACN, SCH, BANF, merlin-1
Previous namesneurofibromin 2 (bilateral acoustic neuroma), neurofibromin 2 (merlin)
Alias namesmoesin-ezrin-radixin like, schwannomin, bilateral acoustic neurofibromatosis

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neoplastic Syndromes, Hereditary
Inherited cancer-predisposing syndrome
Meningioma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

A-kinase anchoring proteinsFERM domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-03-15.
Open TargetsGene–disease associations from the Open Targets Platform.