Back to discover

NHERF4

Gene

NHERF family PDZ scaffold protein 4

HGNCHGNC:19891EnsemblENSG00000172367NCBI Gene79849
Locus: gene with protein productLocation: 11q23.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPDZK2 · PDZD3 · FLJ22756 · IKEPP · NaPi-Cap2
View full nomenclature history (10)
Previous symbolsPDZK2, PDZD3
Alias symbolsFLJ22756, IKEPP, NaPi-Cap2
Previous namesPDZ domain containing 2, PDZ domain containing 3
Alias namesNa/Pi cotransporter C-terminal-associated protein 2, Na(+)/H(+) exchange regulatory cofactor 4, Intestinal and kidney-enriched PDZ protein

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Gastroenteritis
Skin Diseases
Barrett Esophagus
Familial lipoprotein lipase deficiency
Gastric carcinoma
Colitis, Ulcerative
Carcinoma, Renal Cell

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

PDZ domain containingNHERF family PDZ scaffold proteins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.