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NPRL2

Gene

NPR2 like, GATOR1 complex subunit

HGNCHGNC:24969EnsemblENSG00000114388NCBI Gene10641
Locus: gene with protein productLocation: 3p21.31

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asTUSC4 · NPR2L · NPR2
View full nomenclature history (5)
Previous symbolsTUSC4
Alias symbolsNPR2L, NPR2
Previous namestumor suppressor candidate 4, nitrogen permease regulator-like 2 (S. cerevisiae)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Familial focal epilepsy with variable foci
Genetic Diseases, Inborn
Neurodegenerative Diseases
Epilepsies, Partial
Neoplasms
Carcinoma, Hepatocellular
Colorectal Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

GATOR1 subcomplex

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.