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ORC4

Gene

origin recognition complex subunit 4

HGNCHGNC:8490EnsemblENSG00000115947NCBI Gene5000
Locus: gene with protein productLocation: 2q23.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asORC4L · HsORC4 · Orc4p
View full nomenclature history (8)
Previous symbolsORC4L
Alias symbolsHsORC4, Orc4p
Previous namesorigin recognition complex, subunit 4 (yeast homolog)-like, origin recognition complex, subunit 4-like (S. cerevisiae), origin recognition complex, subunit 4 homolog (S. cerevisiae), origin recognition complex, subunit 4, origin recognition complex, subunit 4-like (yeast)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Microcephalic primordial dwarfism
Atrial Fibrillation
Gout
Hypertension, Pregnancy-Induced
Genetic Diseases, Inborn
Coronary Artery Disease
Major depressive disorder

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

AAA ATPasesOrigin recognition complex

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.