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OSGEP

Gene

O-sialoglycoprotein endopeptidase

HGNCHGNC:18028EnsemblENSG00000092094NCBI Gene55644
Locus: gene with protein productLocation: 14q11.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPRSMG1 · GCPL1 · OSGEP1 · KAE1 · TCS3
View full nomenclature history (5)
Alias symbolsPRSMG1, GCPL1, OSGEP1, KAE1, TCS3

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases
Genetic Diseases, Inborn
Neurodevelopmental Disorders
Nephrotic Syndrome
Retinitis Pigmentosa
Congenital glaucoma
Early-onset non-syndromic cataract

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

KEOPS complex

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.