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OTP

Gene

orthopedia homeobox

HGNCHGNC:8518EnsemblENSG00000171540NCBI Gene23440
Locus: gene with protein productLocation: 5q14.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

View full nomenclature history (1)
Previous namesorthopedia homolog (Drosophila)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Gastrointestinal Diseases
Obesity due to melanocortin 4 receptor deficiency
Carcinoid Tumor
Neoplasms
Tinea
Central Nervous System Neoplasms
Non-acquired isolated growth hormone deficiency
Bilateral striopallidodentate calcinosis

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

PRD class homeoboxes and pseudogenes

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.