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P3H1

Gene

prolyl 3-hydroxylase 1

HGNCHGNC:19316EnsemblENSG00000117385NCBI Gene64175
Locus: gene with protein productLocation: 1p34.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asLEPRE1 · GROS1 · LEPRECAN · MGC117314
View full nomenclature history (7)
Previous symbolsLEPRE1
Alias symbolsGROS1, LEPRECAN, MGC117314
Previous namesleucine proline-enriched proteoglycan (leprecan) 1
Alias namesgrowth suppressor 1, procollagen-proline 3-dioxygenase

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Osteogenesis Imperfecta
Genetic Diseases, Inborn
Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Iron (II) and 2-oxoglutarate dependent oxygenasesProlyl 3-hydroxylase family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.