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PAX5

Gene

paired box 5

HGNCHGNC:8619EnsemblENSG00000196092NCBI Gene5079
Locus: gene with protein productLocation: 9p13.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asBSAP · PAX-5
View full nomenclature history (5)
Alias symbolsBSAP, PAX-5
Previous namespaired box gene 5 (B-cell lineage specific activator protein), paired box gene 5 (B-cell lineage specific activator)
Alias namesB-cell lineage specific activator

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Neurodegenerative Diseases
Neurodevelopmental Disorders
Major depressive disorder
Genetic Diseases, Inborn
Prostate adenocarcinoma
Sleep Initiation and Maintenance Disorders
Bipolar Disorder
B-cell acute lymphoblastic leukemia

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

PRD class homeoboxes and pseudogenesPaired boxesMicroRNA protein coding host genes

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.