PDCD1LG2

Gene

programmed cell death 1 ligand 2

HGNCHGNC:18731 EnsemblENSG00000197646 NCBI Gene80380

Locus: gene with protein productLocation: 9p24.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPD-L2 · Btdc · PDL2 · bA574F11.2 · CD273 · B7-DC · B7DC

View full nomenclature history (8)

Alias symbolsPD-L2, Btdc, PDL2, bA574F11.2, CD273, B7-DC, B7DC

Alias namesB7 dendritic cell molecule

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Melanoma

Gastrointestinal Stromal Tumors

Prostate adenocarcinoma

Lymphoid neoplasm

Carcinoma of liver and intrahepatic biliary tract

Carcinoma, Ductal, Breast

HER2 positive breast carcinoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

CD moleculesReceptor ligandsImmunoglobulin like domain containingB7 family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.