PDZK1

Gene

PDZ domain containing 1

HGNCHGNC:8821 EnsemblENSG00000174827 NCBI Gene5174

Locus: gene with protein productLocation: 1q21.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPDZD1 · NHERF3 · CAP70 · CLAMP · NaPi-Cap1

View full nomenclature history (9)

Alias symbolsPDZD1, NHERF3, CAP70, CLAMP, NaPi-Cap1

Alias namesNa/Pi cotransporter C-terminal-associated protein 1, Na(+)/H(+) exchange regulatory cofactor 3, CFTR-associated protein of 70 kDa, C-terminal-linking and modulating protein

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Gout

Hyperuricemia

Neurodegenerative Diseases

Carcinoma, Hepatocellular

Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

PDZ domain containingNHERF family PDZ scaffold proteins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.