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PER1

Gene

period circadian regulator 1

HGNCHGNC:8845EnsemblENSG00000179094NCBI Gene5187
Locus: gene with protein productLocation: 17p13.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPER · RIGUI
View full nomenclature history (5)
Previous symbolsPER
Alias symbolsRIGUI
Previous namesperiod (Drosophila) homolog 1, period homolog 1 (Drosophila), period circadian clock 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Lung carcinoma
Cutaneous melanoma
Skin squamous cell carcinoma
Astrocytoma
Colorectal adenocarcinoma
Gastric carcinoma
Hemangioblastoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

MicroRNA protein coding host genesPAS domain containingPeriod circadian regulator family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.