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PHC2

Gene

polyhomeotic homolog 2

HGNCHGNC:3183EnsemblENSG00000134686NCBI Gene1912
Locus: gene with protein productLocation: 1p35.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asEDR2 · HPH2
View full nomenclature history (5)
Previous symbolsEDR2
Alias symbolsHPH2
Previous namesearly development regulator 2 (homolog of polyhomeotic 2), polyhomeotic-like 2 (Drosophila), polyhomeotic homolog 2 (Drosophila)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases
Smoking initiation
Risk-taking behaviour
Albuminuria
Attention Deficit Disorder with Hyperactivity
Schizophrenia

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Sterile alpha motif domain containingMicroRNA protein coding host genes

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.