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PHOX2B

Gene

paired like homeobox 2B

HGNCHGNC:9143EnsemblENSG00000109132NCBI Gene8929
Locus: gene with protein productLocation: 4p13

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPMX2B · NBPhox
View full nomenclature history (4)
Previous symbolsPMX2B
Alias symbolsNBPhox
Previous namespaired mesoderm homeobox 2b, paired like homeobox 2b

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neuroblastoma
Inherited cancer-predisposing syndrome
Neoplastic Syndromes, Hereditary
Sudden infant death syndrome

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

PRD class homeoboxes and pseudogenes

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.