PHPT1

Gene

phosphohistidine phosphatase 1

HGNCHGNC:30033 EnsemblENSG00000054148 NCBI Gene29085

Locus: gene with protein productLocation: 9q34.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPHP14 · HSPC141 · CGI-202 · DKFZp564M173 · bA216L13.10

View full nomenclature history (7)

Alias symbolsPHP14, HSPC141, CGI-202, DKFZp564M173, bA216L13.10

Alias namesphosphohistidine phosphatase 14kDa, sex-regulated protein janus-a

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Lung carcinoma

Lung Neoplasms

hyperinsulinism due to INSR deficiency

Metabolic Syndrome

Pulmonary Disease, Chronic Obstructive

autosomal dominant hyperinsulinism due to Kir6.2 deficiency

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Protein phosphatases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.