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PIDD1

Gene

p53-induced death domain protein 1

HGNCHGNC:16491EnsemblENSG00000177595NCBI Gene55367
Locus: gene with protein productLocation: 11p15.5

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asLRDD · PIDD · MGC16925 · DKFZp434D229
View full nomenclature history (6)
Previous symbolsLRDD, PIDD
Alias symbolsMGC16925, DKFZp434D229
Previous namesleucine-rich repeats and death domain containing, p53-induced death domain protein

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Autistic Disorder
Psychotic disorder

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

ZU5 domain containingCaspase-2 PIDDosome complex

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-03-15.
Open TargetsGene–disease associations from the Open Targets Platform.