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PIGQ

Gene

phosphatidylinositol glycan anchor biosynthesis class Q

HGNCHGNC:14135EnsemblENSG00000007541NCBI Gene9091
Locus: gene with protein productLocation: 16p13.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known ashGPI1 · GPI1
View full nomenclature history (4)
Alias symbolshGPI1, GPI1
Previous namesphosphatidylinositol glycan, class Q
Alias namesPhosphatidylinositol N-acetylglucosaminyltransferase subunit Q

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Genetic developmental and epileptic encephalopathy
Epilepsy
Genetic Diseases, Inborn
early-infantile DEE
Neurodegenerative Diseases
Optic Atrophy
Retinitis Pigmentosa

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Phosphatidylinositol glycan anchor biosynthesisGlycosylphosphatidylinositol-N-acetylglucosaminyltransferase complex

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.