PIK3CD

Gene

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta

HGNCHGNC:8977 EnsemblENSG00000171608 NCBI Gene5293

Locus: gene with protein productLocation: 1p36.22

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformO00329

Protein · therapeutic target

Clinically validated target · 10 approved medicines against this target

Member of “Class Ia Phosphatidylinositol 3-Kinase” · 1 related family paper (context, not papers about this gene)

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asp110D

View full nomenclature history (5)

Alias symbolsp110D

Previous namesphosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta, phosphoinositide-3-kinase, catalytic, delta polypeptide

Alias namesphosphatidylinositol 3-kinase, catalytic, delta polypeptide, phosphoinositide-3-kinase C

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Leukemia, Lymphocytic, Chronic, B-Cell

Lymphoma, Follicular

Neoplasms

Lymphoma, Non-Hodgkin's

Marginal zone lymphoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Phosphatidylinositol 3-kinase family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.