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PKD2

Gene

polycystin 2, transient receptor potential cation channel

HGNCHGNC:9009EnsemblENSG00000118762NCBI Gene5311
Locus: gene with protein productLocation: 4q22.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPKD4 · PC2 · Pc-2 · TRPP2
View full nomenclature history (6)
Alias symbolsPKD4, PC2, Pc-2, TRPP2
Previous namespolycystic kidney disease 2 (autosomal dominant)
Alias namestransient receptor potential cation channel, subfamily P, member 2

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Polycystic Kidney, Autosomal Dominant
Polycystic Kidney Diseases
Kidney Failure, Chronic
Kidney Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Transient receptor potential cation channelsEF-hand domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.