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PKP4

Gene

plakophilin 4

HGNCHGNC:9026EnsemblENSG00000144283NCBI Gene8502
Locus: gene with protein productLocation: 2q24.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asp0071
View full nomenclature history (1)
Alias symbolsp0071

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Hypertension
Smoking initiation
bone Paget's disease
Restless Legs Syndrome
Obesity disorder
Essential Hypertension
Substance-Related Disorders
Cardiovascular Diseases
Sleep Initiation and Maintenance Disorders

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Armadillo repeat containingp120 catenin family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.