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PLOD1

Gene

procollagen-lysine,2-oxoglutarate 5-dioxygenase 1

HGNCHGNC:9081EnsemblENSG00000083444NCBI Gene5351
Locus: gene with protein productLocation: 1p36.22

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asLLH · PLOD · LH1
View full nomenclature history (6)
Previous symbolsLLH, PLOD
Alias symbolsLH1
Previous namesprocollagen-lysine 1, 2-oxoglutarate 5-dioxygenase (lysine hydroxylase, Ehlers-Danlos syndrome type VI)
Alias nameslysyl hydroxlase 1, procollagen lysyl hydroxylase 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Ehlers-Danlos Syndrome
Neurodegenerative Diseases
Cryptorchidism

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Procollagen-lysine,2-oxoglutarate 5-dioxygenase family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.