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POLH

Gene

DNA polymerase eta

HGNCHGNC:9181EnsemblENSG00000170734NCBI Gene5429
Locus: gene with protein productLocation: 6p21.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asXPV · RAD30A · XP-V
View full nomenclature history (5)
Alias symbolsXPV, RAD30A, XP-V
Previous namespolymerase (DNA directed), eta, polymerase (DNA) eta

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Xeroderma Pigmentosum
Genetic Diseases, Inborn
Carcinoma, Hepatocellular
Leukemia, Myeloid, Acute
Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

DNA polymerasesXeroderma pigmentosum complementation groupsZinc fingers UBZ3 CCHH-type

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2026-02-09.
Open TargetsGene–disease associations from the Open Targets Platform.