POLK

Gene

DNA polymerase kappa

HGNCHGNC:9183 EnsemblENSG00000122008 NCBI Gene51426

Locus: gene with protein productLocation: 5q13.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asDINB1 · POLQ · DINP

View full nomenclature history (7)

Previous symbolsDINB1

Alias symbolsPOLQ, DINP

Previous namespolymerase (DNA directed) kappa, polymerase (DNA) kappa

Alias namesDINB protein, DNA polymerase kappa

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Familial prostate cancer

Prostatic Neoplasms

Sleep Apnea, Obstructive

Genetic Diseases, Inborn

Diabetes Mellitus, Type 2

Central Nervous System Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

DNA polymerasesZinc fingers UBZ4 CCHC-type

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.