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POT1

Gene

protection of telomeres 1

HGNCHGNC:17284EnsemblENSG00000128513NCBI Gene25913
Locus: gene with protein productLocation: 7q31.33

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known ashPot1 · DKFZp586D211
View full nomenclature history (3)
Alias symbolshPot1, DKFZp586D211
Previous namesprotection of telomeres 1 homolog (S. pombe)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Leukemia, Lymphocytic, Chronic, B-Cell
Familial melanoma
Inherited cancer-predisposing syndrome
Neoplastic Syndromes, Hereditary
Neurodegenerative Diseases
Multiple Myeloma
Lung carcinoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Shelterin complex

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-03-15.
Open TargetsGene–disease associations from the Open Targets Platform.