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POU1F1

Gene

POU class 1 homeobox 1

HGNCHGNC:9210EnsemblENSG00000064835NCBI Gene5449
Locus: gene with protein productLocation: 3p11.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPIT1 · GHF-1 · POU1F1a · PIT-1
View full nomenclature history (7)
Previous symbolsPIT1
Alias symbolsGHF-1, POU1F1a, PIT-1
Previous namesPOU domain class 1, transcription factor 1
Alias namesgrowth hormone factor 1, pituitary transcript factor 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Genetic Diseases, Inborn
Prostate carcinoma
Congenital Hypothyroidism
Prostatic Neoplasms
Intestinal Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

POU class homeoboxes and pseudogenes

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.