PPP1CB

Gene

protein phosphatase 1 catalytic subunit beta

HGNCHGNC:9282 EnsemblENSG00000213639 NCBI Gene5500

Locus: gene with protein productLocation: 2p23.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPP1Cbeta · PPP1CD · PP1Cdelta · PP1B · PP-1B · PP1beta · PP1c · MP · PPP1beta

View full nomenclature history (13)

Alias symbolsPP1Cbeta, PPP1CD, PP1Cdelta, PP1B, PP-1B, PP1beta, PP1c, MP, PPP1beta

Previous namesprotein phosphatase 1, catalytic subunit, beta isoform, protein phosphatase 1, catalytic subunit, beta isozyme

Alias namesprotein phosphatase 1, catalytic subunit, delta isozyme, myosin phosphatase

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Noonan syndrome

Neurodegenerative Diseases

RASopathy

Autoimmune disorder of central nervous system

Genetic Diseases, Inborn

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Protein phosphatase catalytic subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2026-02-10.

Open TargetsGene–disease associations from the Open Targets Platform.