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PRKACA

Gene

protein kinase cAMP-activated catalytic subunit alpha

HGNCHGNC:9380EnsemblENSG00000072062NCBI Gene5566
Locus: gene with protein productLocation: 19p13.12

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPKACa
View full nomenclature history (5)
Alias symbolsPKACa
Previous namesprotein kinase, cAMP-dependent, catalytic, alpha, protein kinase, cAMP-dependent, alpha catalytic subunit
Alias namescAMP-dependent protein kinase catalytic subunit alpha, PKA C-alpha

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Adenoma, Liver Cell

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Protein kinase A subunitsProtein kinase A family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-10-31.
Open TargetsGene–disease associations from the Open Targets Platform.