PRSS22

Gene

serine protease 22

HGNCHGNC:14368 EnsemblENSG00000005001 NCBI Gene64063

Locus: gene with protein productLocation: 16p13.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known ashBSSP-4 · BSSP-4 · SP001LA

View full nomenclature history (5)

Alias symbolshBSSP-4, BSSP-4, SP001LA

Previous namesprotease, serine 22

Alias namesbrain-specific serine protease 4

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Erythematosquamous dermatosis

Dermatitis, Seborrheic

Familial prostate cancer

Prostatic Neoplasms

Neoplasms

Breast Neoplasms

Carcinoma, Hepatocellular

Stomach Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Serine proteases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.