PSMB9

Gene

proteasome 20S subunit beta 9

HGNCHGNC:9546 EnsemblENSG00000240065 NCBI Gene5698

Locus: gene with protein productLocation: 6p21.32

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Proteasome subunit beta type-9P28065

Protein · therapeutic target

Clinically validated target · 5 approved medicines against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asLMP2 · RING12 · beta1i · PSMB6i

View full nomenclature history (9)

Previous symbolsLMP2

Alias symbolsRING12, beta1i, PSMB6i

Previous namesproteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional protease 2), large multifunctional peptidase 2, proteasome (prosome, macropain) subunit, beta type, 9, proteasome subunit beta 9

Alias namesproteasome subunit β1i

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Multiple Myeloma

Lymphoma, Mantle-Cell

Neoplasms

Immunoglobulin Light-chain Amyloidosis

Precursor Cell Lymphoblastic Leukemia-Lymphoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Proteasome

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.