Back to discover

PTGER3

Gene

prostaglandin E receptor 3

HGNCHGNC:9595EnsemblENSG00000050628NCBI Gene5733
Locus: gene with protein productLocation: 1p31.1

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Prostaglandin E2 receptor EP3 subtypeP43115

Protein · therapeutic target

Clinically validated target · 2 approved medicines against this target

Member of “Receptors, Prostaglandin” · 1 related family paper (context, not papers about this gene)

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asEP3 · lnc003875
View full nomenclature history (3)
Alias symbolsEP3, lnc003875
Previous namesprostaglandin E receptor 3 (subtype EP3)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Arthritis, Rheumatoid
Gastroesophageal Reflux
Neurodegenerative Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Prostaglandin receptors

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-03-15.
Open TargetsGene–disease associations from the Open Targets Platform.