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RAG1

Gene

recombination activating 1

HGNCHGNC:9831EnsemblENSG00000166349NCBI Gene5896
Locus: gene with protein productLocation: 11p12

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asMGC43321 · RNF74
View full nomenclature history (6)
Alias symbolsMGC43321, RNF74
Previous namesrecombination activating gene 1
Alias namesV(D)J recombination-activating protein 1, recombination activating protein 1, RING finger protein 74

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Severe Combined Immunodeficiency
T-B- severe combined immunodeficiency

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Ring finger proteinsRAG transposon derived genes

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.