RASA1

Gene

RAS p21 protein activator 1

HGNCHGNC:9871 EnsemblENSG00000145715 NCBI Gene5921

Locus: gene with protein productLocation: 5q14.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asRASA · GAP · CM-AVM · p120GAP · p120RASGAP · p120

View full nomenclature history (10)

Previous symbolsRASA

Alias symbolsGAP, CM-AVM, p120GAP, p120RASGAP, p120

Previous namesRAS p21 protein activator (GTPase activating protein) 1

Alias namescapillary malformation-arteriovenous malformation, p120 RAS GTPase activating protein, Ras GTPase-activating protein 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Vascular Malformations

Basal cell carcinoma

Squamous cell lung carcinoma

Neurodegenerative Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Pleckstrin homology domain containingSH2 domain containingC2 and RasGAP domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.