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REG4

Gene

regenerating family member 4

HGNCHGNC:22977EnsemblENSG00000134193NCBI Gene83998
Locus: gene with protein productLocation: 1p12

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asREG-IV · RELP · GISP
View full nomenclature history (6)
Alias symbolsREG-IV, RELP, GISP
Previous namesregenerating islet-derived family, member 4
Alias namesregenerating gene type IV, gastrointestinal secretory protein

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Cutaneous lupus erythematosus
Pneumonia
Lung Diseases, Fungal
Barrett Esophagus
Obesity disorder
Obesity due to melanocortin 4 receptor deficiency
Colonic Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

C-type lectin domain containingRegenerating family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.