REV3L

Gene

REV3 like, DNA directed polymerase zeta catalytic subunit

HGNCHGNC:9968 EnsemblENSG00000009413 NCBI Gene5980

Locus: gene with protein productLocation: 6q21

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPOLZ · REV3

View full nomenclature history (6)

Alias symbolsPOLZ, REV3

Previous namesREV3 (yeast homolog)-like, catalytic subunit of DNA polymerase zeta, REV3-like, catalytic subunit of DNA polymerase zeta (yeast), REV3-like, polymerase (DNA directed), zeta, catalytic subunit

Alias namespolymerase, DNA, zeta

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Smoking initiation

Risk-taking behaviour

Diabetes Mellitus, Type 2

Schizophrenia

Psoriasis

Placental retention

Attention Deficit Disorder with Hyperactivity

Substance-Related Disorders

Marijuana Abuse

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

DNA polymerases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.