RFC1

Gene

replication factor C subunit 1

HGNCHGNC:9969 EnsemblENSG00000035928 NCBI Gene5981

Locus: gene with protein productLocation: 4p14

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asA1 · PO-GA · RFC140 · MHCBFB

View full nomenclature history (6)

Alias symbolsA1, PO-GA, RFC140, MHCBFB

Previous namesreplication factor C (activator 1) 1 (145kD), replication factor C (activator 1) 1, 145kDa

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

AAA ATPasesReplication factor C

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.